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designed for and administered by nonprofessional  产品科学验证*
          29.  Wookey, V., et al., Subjective evaluation of   44.  Whittam, J.H., et al., Weight management program
            satiety after fiber consumption. Wooky, Jensen,
            Moshrefi, Spiller. Fed Proc, 1986;45:A2575(abstr).   leaders. 4th European Nutrition Conference, 1983.
            Fed Proc, 1986. 45(3): p. 597.
                                          45.  Whittam, J.H., et al., Weight loss on a combined   NUTRITION
          30.  Jensen, C.D., et al., Observations on the   regimen of formula diet and traditional food. 4th   SUBJECT: 12-HOUR CALCIUM
            effects in humans of cis- and trans-b-carotene   International Conference on Obesity, 1983.
            isomers. Am J Clin Nutr, 1986. 43(4): p. 689.  46.  Albanese, A.A., et al., Effects of vitamin/  BIOAVAILABILITY STUDY
          31.  Spiller, G.A., et al., Effect on protein   mineral intervention on increasing bone   This study assessed the serum and urine response
            quantity and quality on the serum glucose   density of postmenopausal women. 4th   during the initial 12 hours after the ingestion of a new
                                                                                                    ®
            response to the sugars of a formula diet.   European Nutrition Conference, 1983.  calcium formulation found in Shaklee OsteoMatrix .
            Am J Clin Nutr, 1985. 41(4): p. 854.                          Changes in serum calcium were measured at nine time
                                          47.  Story, J.A., et al., Modification of human   points (0 hr, 1 hr, 2 hr, 3 hr, 4 hr, 5 hr, 6 hr, 8 hr, and 12
          32.  Spiller, G.A., et al., Some effects of vitamin   fecal steroid excretion by a dietary fiber   hr) during the initial 12 hours following ingestion of
            and mineral supplementation in healthy young   supplement. Fed Proc, 1983. 42(4): p. 1062.  two tablets containing a total of 500 mg calcium. At
            women. Fed Proc, 1985. 44(4): p. 1283.                        carefully timed intervals, within minutes of providing
                                          48.  Spallholz, J.E., et al., Cytotoxic activity of selenium
          33.  Story, J.A., et al., Modification of fecal steroid   compounds and glutathione peroxidase assessed   a baseline blood sample, 10 healthy volunteers
            excretion in humans by hard red wheat bran.   by scanning electron microscopy. Fed Proc, 1982.   ingested two supplement tablets with 125 mL of water.
            XIII International Congress of Nutrition, 1985.  41(3): p. 529.   Results from the serum calcium assays on samples
                                                                          collected during the 12 hours immediately following
          34.  Pattison, T.S., et al., Comparison of serum                supplementation were compared to each other and
            carotene repletion with two levels of carrots   49.  Chuck, C.S., et al., Postprandial glycemia   to the baseline serum calcium levels. The net changes
            and an algae-derived product in healthy adult   on two sweet confections with different   in serum calcium during the 12 hours immediately
            humans. Fed Proc, 1985. 44(3): p. 771.  carbohydrate patterns. Fed Proc, 1982. 41(398).  following supplementation are presented graphically in
          35.  Scala, J. and L. Wong, The coach and   50.  Pattison, T., R. Allen, and H. Ashley, Automated   the figure below:
            nutritionist—a partnership in performance.   testing of slowly changing levels of analytes in   Peningkatan Bersih Serum Kalsium
            Nutrition in Sport, ed. O.H. Shrimpton and   mixtures. Clin Chem, 1982. 28(7): p. 1613.  0.6
            P.B. Ottaway. 1985, London. 76-83.
                                          51.  Soparkar, P.M., et al., Clinical study of the   PLACEBO
          36.  Spiller, G.A., et al., Effect on postprandial   effect of an organic dentifrice on gingivitis and   0.4  (FLAVORED   200 + 2
                                                                                  WATER)
            glycemia of a formula diet and its carbohydrate   plaque formation. J Dent Res, 1980. 59(275).  Serum Calcium (mg/dL) Serum Kalsium (mg/dL)
            fraction with or without protein and fat.   52.  Poovaiah, B.P., J.A. Rider, and J. Scala, The kinetics
            AM J Clin Nutr, 1984. 39(4): p. 671.                              0.2  PERFORMANCE  200 +  33
                                            of vitamin C in human blood plasma from vitamin
          37.  Dronkert, A. and G.A. Spiller, Safety and effect   C supplements. Fed Proc, 1980. 39(3): p. 557.
                                                                                   MINUTES CYCLING
            on weight, hemoglobin A-1C, serum glucose                         0.0  (45% to 75% VO 2  max)  MINUTES TIL FATIGUE
                                                                                           (80% of  VO 2  max)
            and blood pressure of a liquid formula diet   53.  Albanese, A.A., et al., Effects of calcium   0  2  4  6  8  10  12
                                            and micronutrients on premenopausal
            combined with traditional food in adult diabetic   and postmenopausal bone loss.   Masa dalam Jam
            patients: A pilot study. The 5th International   JAMA, 1980. 244(17): p. 1915.  These results indicate that the net increase in serum calcium levels of
            Congress of Diabetes and Nutrition, 1984.                     the volunteers increased during the initial 5 hours
                                          54.  Newman, M.B., et al., Clinical study of   after supplementation and then slowly decreased through
          38.  Wei, H., et al., Effect of selenium supplements   the effectiveness of an organic dentifrice   the 12-hour monitoring period. A comparison of the net changes in
            on the selenium levels and glutathione   for stain removal. American Associations   serum calcium during the first 12 hours following
            peroxidase activity of residents in a selenium-  for Dental Research, 1980. 59: p. 276.    supplementation (ANOVA) determined that significant differences
            deficient area of hebei province, people’s                    in the net increase of serum calcium from baseline occurred from 2 to
            republic of China. Fed Proc, 1984. 43(473).                   12 postcalcium ingestion (P<.05).  These data demonstrate that the
                                                                          calcium provided in OsteoMatrix is well absorbed during the initial 12
          39.  Luo, X., et al., Selenium intake and metabolic             hours following ingestion.
            balance in 10 men consuming self-selected diets
            in a selenium-deficient area of hebei province,               WEIGHT MANAGEMENT
            people’s republic of China. Fed Proc, 1984. 43(473).          SUBJECT: SHAKLEE 180   ®
          40. Spiller, G.A., et al., Effect of four levels of hard        WEIGHT-LOSS PROGRAM
            wheat bran on fecal composition and transit time              CLINICAL STUDY: SHAKLEE 180 12-WEEK
            in healthy young women. Fed Proc, 1984. 43(392).              SAFETY AND EFFICACY PILOT STUDY
          41.  Spiller, G.A., et al., Postpranial    hyperglycemia           This pilot study was designed to determine
            in a complete liquid formula diet, its carbohydrate           changes in weight loss, anthropometric
            fraction and glucose. The 4th International                   measurements, and estimates of body
            Congress of Diabetes and Nutrition, 1983.                     composition in an uncontrolled 12-week
          42.  Hoage, C.M. and M.E. Fediuk, Compulsive                    trial with 27 moderately overweight, but
            eating, depression and failure to complete a                  otherwise healthy, men and women. Subjects were
                                                                                              ®
            behavioral group weight loss program. 4th                     instructed to consume two Shaklee 180  beverage
                                                                                       ®
            International Congress on Obesity, 1983.                      shakes, three Shaklee 180  dietary    ®
                                                                          supplement tablets, one Shaklee 180  nutrition bar, and a
          43.  Minear, A.L., G.M. Blankenbaker, and P.V.                  healthy meal and/or snack daily.
            Sacks, 630 Kcal formula diet Versus 1,200 Kcal                   Eighteen participants completed the 12-week trial, of
            balanced deficit diet: comparison of weight                   which 14 were fully compliant. Data from 14 participants
            loss and safety. J Am Diet Assoc, 1983. 83.
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